Nanotechnology describes precision manufacturing of materials at the nano scale. Nanotechnology has a vast range of applications, such as medicines, electronics, biomaterials and energy production. The present research work is a green eco-friendly approach to the production of gold nanoparticles (Au-NPs) by using the plant extract of Cannabis sativa. The appearance of a ruby-red color from a greenish color is the primary indication of the formation of Au-NPs. C. sativa contains some active compounds that were found to be responsible for the reduction of gold and converting it into a bioactive metal. The synthesized Au-NPs were characterized by ultraviolet–visible spectroscopy, high-resolution scanning electron microscopy and Fourier transform infrared spectroscopy. In vitro antimicrobial, cytotoxicity, biocompatibility and enzyme inhibition assays were performed. Notable antimicrobial activities are reported. Bioinspired Au-NPs were found effective against bacterial and fungal strains. A 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was performed to check the leishmanicidal activity against amastigotes (IC₅₀: 171·00 ± 2·28 μg/ml) of Leishmania tropica. Brine shrimp lethality was also shown by the bioinspired Au-NPs. Furthermore, substantial protein kinase inhibition was noted.

中文翻译：

---

大麻苜蓿介导的金纳米粒子的合成及其生物医学特性

纳米技术描述了纳米级材料的精密制造。纳米技术具有广泛的应用，例如药物，电子，生物材料和能源生产。目前的研究工作是使用大麻植物提取物生产金纳米颗粒（Au-NPs）的绿色环保方法。呈红绿色的红宝石色的外观是Au-NPs形成的主要指示。苜蓿包含一些活性化合物，这些化合物被发现可以还原金并将其转化为生物活性金属。通过紫外可见光谱，高分辨率扫描电子显微镜和傅里叶变换红外光谱对合成的金纳米粒子进行了表征。进行了体外抗菌，细胞毒性，生物相容性和酶抑制试验。报告了显着的抗菌活性。发现具有生物启发性的Au-NP对细菌和真菌菌株有效。进行了3-（4,5-二甲基噻唑-2-基）-2,5-二苯基四唑溴化物（MTT）分析，以检查其对Amastigotes（IC ₅₀：171·00±2· 28μg / ml）的杀利害活性。热带利什曼原虫。受生物启发的金纳米颗粒还显示了盐水虾的致死性。此外，注意到显着的蛋白激酶抑制作用。