Abstract: In recent years, it has been found that exosomes can be used as nanocarriers, which can be used in the treatment of tumors by carrying contents. The exosomes are derived from the secretion of the organism’s own cells and are characterized by a phospholipid bilayer structure and a small particle size. These characteristics guarantee that the exosomes can carry a wide range of tumor drugs, deliver the drug to the cancer, and reduce or eliminate the tumor drug band. The toxic side effects were significantly eliminated; meanwhile, the therapeutic effects of the drug on the tumor were remarkably improved. This paper reviewed the strategies and drugs presented by different scholars for the treatment of tumors based on the drugs carried by exosomes.

Keywords: exosomes, nanocarriers, function, tumor therapy


中文翻译：

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外泌体作为癌症治疗的主动靶向纳米载体。


摘要：近年来发现外泌体可以作为纳米载体，通过携带内容物用于肿瘤的治疗。外泌体来源于生物体自身细胞的分泌物，具有磷脂双层结构和粒径小的特点。这些特性保证了外泌体可以携带多种肿瘤药物，将药物递送至癌症，减少或消除肿瘤药物带。毒副作用显着消除；同时，药物对肿瘤的治疗效果也显着提高。本文综述了不同学者基于外泌体携带的药物提出的治疗肿瘤的策略和药物。


关键词：外泌体，纳米载体，功能，肿瘤治疗