当前位置: X-MOL 学术Heteroat. Chem. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Synthesis of Some New 1,2,4-Triazine and 1,2,5-Oxadiazine Derivatives with Antimicrobial Activity
Heteroatom Chemistry ( IF 1.1 ) Pub Date : 2019-09-25 , DOI: 10.1155/2019/2326514
Heba E. Hashem 1 , Ahmed M. Abo-Bakr 2
Affiliation  

1,2,4-Triazine and 1,2,5-oxadiazine derivatives 2–12 were obtained from treated 1,3-oxazolone (1) with phenyl hydrazine or hydroxylamine hydrochloride. Chlorotriazine derivative 3 undergoing condensation reactions with different reagents produced new fused tetrazolo-triazine and triazino-quinazolinone derivatives. 1,2,5-Oxadiazine has been used as a synthon for the fused pyrazolo-oxadiazine derivative. The constitution of the prepared compounds was built up based on microanalytical and spectral data. Some of the new compounds were assessed for their antimicrobial activity.

中文翻译:

一些具有抗菌活性的新型 1,2,4-三嗪和 1,2,5-恶二嗪衍生物的合成

1,2,4-三嗪和 1,2,5-恶二嗪衍生物 2-12 是从用苯肼或盐酸羟胺处理的 1,3-恶唑酮 (1) 中获得的。氯三嗪衍生物 3 与不同试剂发生缩合反应,生成新的稠合四唑并三嗪和三嗪基喹唑啉酮衍生物。1,2,5-恶二嗪已被用作稠合吡唑并恶二嗪衍生物的合成子。所制备化合物的组成是基于微量分析和光谱数据建立的。对一些新化合物的抗菌活性进行了评估。
更新日期:2019-09-25
down
wechat
bug