Microfluidic devices have been widely applied to trapping and isolation of cells and clusters for controllable intercellular environments and high-throughput analysis, triggering numerous advances in disease diagnosis and single-cell analysis. Passive hydrodynamic cell trapping is one of the simple and effective methods that has been gaining attention in recent years. Our aim here is to review the existing passive microfluidic trapping approaches, including microposts, microfiltration, microwells, and trapping chambers, with emphasis on design principles and performance. We summarize the remarkable advances that hydrodynamic trapping methods offer, as well as the existing challenges and prospects for development. Finally, we hope that an improved understanding of hydrodynamic trapping approaches can lead to sophisticated and useful platforms to advance medical and biological research.

中文翻译：

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用于细胞和簇的流体动力学捕获的微流体系统

微流控装置已广泛应用于捕获和分离细胞和细胞簇，以实现可控的细胞间环境和高通量分析，在疾病诊断和单细胞分析方面取得了许多进展。被动流体动力学细胞捕获是近年来受到关注的简单有效的方法之一。我们的目的是回顾现有的被动微流体捕集方法，包括微柱、微过滤、微孔和捕集室，重点是设计原则和性能。我们总结了水动力捕集方法的显着进步，以及现有的挑战和发展前景。最后，