The SARS-CoV-2 pandemic has prompted scientists from many disciplines to work collaboratively toward an effective response. As academic synthetic chemists, we examine how best to contribute to this ongoing effort. The current pandemic draws comparisons to past global health crises where synthetic chemists have made significant translational contributions through fundamental research. In the context of manufacturing compounds like remdesivir, several research areas are outlined herein which require further development and creativity from chemists in order to drive advances in antiviral research during this time of need. As a community, driving future innovations in synthetic chemistry will be imperative if we are to tackle global health threats such as COVID-19.

中文翻译：

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用合成化学治疗全球健康危机。

SARS-CoV-2 大流行促使多个学科的科学家共同努力，寻求有效的应对措施。作为学术合成化学家，我们研究如何最好地为这一持续的努力做出贡献。当前的大流行与过去的全球健康危机进行了比较，在过去的全球健康危机中，合成化学家通过基础研究做出了重大的转化贡献。在制造瑞德西韦等化合物的背景下，本文概述了几个研究领域，这些领域需要化学家的进一步开发和创造力，以便在这个需要的时期推动抗病毒研究的进展。如果我们要应对 COVID-19 等全球健康威胁，作为一个社区，推动合成化学的未来创新势在必行。