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Co-Designed Exposure Protocol in the Study of Idiopathic Environmental Intolerance Attributed to Electromagnetic Fields.
Bioelectromagnetics ( IF 1.8 ) Pub Date : 2020-06-29 , DOI: 10.1002/bem.22281
Maryse Ledent 1 , Benjamin Vatovez 2 , Willy Pirard 2 , Jimmy Bordarie 3 , Nicolas Prignot 4 , Gunnhild Oftedal 5 , Christophe Geuzaine 6 , Véronique Beauvois 6 , Catherine Bouland 7 , Luc Verschaeve 1 , Maël Dieudonné 8
Affiliation  

The hypothesis of an electromagnetic origin of idiopathic environmental intolerance (IEI) attributed to electromagnetic fields (EMF) has been widely investigated by provocation studies, which consist of deliberately exposing people with IEI‐EMF in laboratory settings to particular EMF to observe volunteers’ reactions. In the majority of these studies, reactions have been found to be independent of exposure. However, most of these studies suffer from design and methodological limitations that might bias their findings or reduce their precision. As provocation studies are best suited for isolating the effects of EMF, innovative protocols should be applied. In the ExpoComm project (PNREST Anses, EST/2017/2 RF/19), several innovations have been introduced: the involvement of people with IEI‐EMF in the development of the protocol, the attenuation of the anxiogenic nature of the tests, the individualization of the protocol, the validation of the neutral or normal reactivity state before the test, and the use of a cocktail of real, rather than artificially generated, sources. The objective of involving people with IEI‐EMF was to increase the relevance and acceptability of the protocol, while respecting technical constraints and scientific quality requirements. This paper describes the protocol resulting from the collaborative process. Bioelectromagnetics. 2020;41:425–437. © 2020 Bioelectromagnetics Society.

中文翻译:

在研究归因于电磁场的特发性环境不宽容方面的共同设计的暴露协议。

激发研究已广泛研究了归因于电磁场(EMF)的特发性环境不耐受(IEI)的电磁起源的假设,包括故意将实验室环境中患有IEI-EMF的人暴露于特定的EMF中以观察志愿者的反应。在大多数这些研究中,已发现反应与暴露无关。但是,这些研究中的大多数都受到设计和方法上的局限,可能会限制其发现或降低其准确性。由于激发研究最适合隔离EMF的影响,因此应采用创新的方案。在ExpoComm项目(PNREST Anses,EST / 2017/2 RF / 19)中,引入了多项创新:IEI‐EMF人员参与协议的开发,测试的抗焦虑作用的减弱,协议的个性化,测试前中性或正常反应状态的验证以及使用真实而非人工来源的混合物。让拥有IEI-EMF的人员参与进来的目的是在尊重技术约束和科学质量要求的同时,提高协议的相关性和可接受性。本文描述了协作过程产生的协议。生物电磁学。2020; 41:425–437。©2020生物电磁学会。让IEI‐EMF人员参与的目的是在尊重技术约束和科学质量要求的同时,提高协议的相关性和可接受性。本文描述了协作过程产生的协议。生物电磁学。2020; 41:425–437。©2020生物电磁学会。让IEI‐EMF人员参与的目的是在尊重技术约束和科学质量要求的同时,提高协议的相关性和可接受性。本文描述了协作过程产生的协议。生物电磁学。2020; 41:425–437。©2020生物电磁学会。
更新日期:2020-08-18
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