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Involvement of the cerebellum in the serial reaction time task (SRT) (Response to Janacsek et al.)
NeuroImage ( IF 4.7 ) Pub Date : 2020-10-01 , DOI: 10.1016/j.neuroimage.2020.117114
Kris Baetens 1 , Mahyar Firouzi 1 , Frank Van Overwalle 1 , Natacha Deroost 1
Affiliation  

An ALE meta-analysis focused on the serial reaction time task published in NeuroImage (Janacsek et al., 2019) demonstrated consistent activation of the basal ganglia across neuroimaging studies featuring sequence > random block contrasts and no consistent cerebellar activation. To enable valid conclusions regarding the role of the cerebellum in this context, some of the included studies should be excluded (e.g., because the cerebellum was explicitly not scanned). After omitting 6 of 16 studies / subject groups, 70% of the remaining studies did report cerebellar activation. While an ALE analysis of the remaining contrasts confirmed the original results, it may lack the power to detect cerebellar effects. We argue the conclusion that the cerebellum is not involved in sequence-specific learning should be treated with caution.

中文翻译:

小脑参与串行反应时间任务 (SRT)(对 Janacsek 等人的回应)

一项 ALE 荟萃分析侧重于 NeuroImage(Janacsek 等人,2019 年)中发表的系列反应时间任务,证明了在神经影像学研究中基底神经节的激活一致,其特点是序列 > 随机块对比,并且没有一致的小脑激活。为了能够得出关于小脑在这种情况下的作用的有效结论,一些纳入的研究应该被排除在外(例如,因为小脑没有明确扫描)。在省略 16 项研究/受试者组中的 6 项后,其余研究中有 70% 确实报告了小脑激活。虽然对剩余对比的 ALE 分析证实了原始结果,但它可能缺乏检测小脑效应的能力。我们认为应该谨慎对待小脑不参与序列特定学习的结论。
更新日期:2020-10-01
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