Solvothermal reactions of 5-methylisophthalic acid (H2mipa) with 1,4-bis(imidazol-1ylmethyl)benzene (1,4-bib) or 1,3-bis(imidazol-1ylmethyl)benzene (1,3-bib) in the presence of Co(NO3)2·6H2O in a mixed solvent of H2O/DMF yielded two new coordination polymers, namely, [Co2(mipa)(1,4-bib)](H2O) (1)and [Co3(Hmipa)2(mipa)2(1,3-bib)](H2tba)(H2O)2 (2). These complexes were characterized by elemental analysis and X-ray single-crystal diffraction, which reveals that complex 1 is mutually interpenetrated each other to form 3D+3D⟶3D interpenetrated framework with crs/dia-e topology, and complex 2 is constructed from the trinuclear [Co3(COO)6] unit connected by tbip ligands to form 1D structures which were extended to form 2D structures by neutral ligands. Furthermore, the anti-ovarian cancer activity of the two coordination complexes has been evaluated via the Cell Counting Kit-8 (CCK-8) assay and western blot assay.

中文翻译：

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基于咪唑基和芳香族二羧酸配体的两种配位聚合物的构建：结构多样性和抗卵巢癌活性研究

5-甲基间苯二甲酸（H2mipa）与1,4-双（咪唑-1基甲基）苯（1,4-bib）或1,3-双（咪唑-1基甲基）苯（1,3-bib）的溶剂热反应在H2O / DMF混合溶剂中Co（NO3）2·6H2O的存在产生了两种新的配位聚合物，即[Co2（mipa）（1,4-bib）]（H2O）（1）和[Co3（Hmipa） 2（mipa）2（1,3-bib）]（H2tba）（H2O）2（2）。通过元素分析和X射线单晶衍射对这些配合物进行表征，发现配合物1相互渗透形成具有crs / dia-e拓扑结构的3D +3D⟶3D互穿框架，而配合物2由三核[Co3（COO）6]单元通过tbip配体连接形成1D结构，并通过中性配体扩展形成2D结构。此外，