Solvothermal reactions of 2,2-bipyridine (2,2-bpy) or 1,10-phenanthroline (1,10-phen) with Bi(NO3)3·5H2O or Ce(NO3)3·6H2O in the presence of different pH modulator afforded two new coordination complexes [Bi2(2,2-bpy)2(BA)6] (1, HBA = benzoic acid) and [Ce(1,10-phen)Cl2]Cl (2). The structures of the two complexes have been characterized by elemental analysis, infrared spectrum and X-ray crystal diffraction. Furthermore, the anticancer activity of the two synthesized complexes has been evaluated via the preformation of the Cell Counting Kit-8 (CCK-8) assays. And the relative expression of the inflammatory response genes p53, nf-κb, and tnf-α was detected by reverse transcriotion-polymerase chain reaction (RT-PCR).

中文翻译：

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两种新的含Bi（III）和Ce（III）的配位复合物：神经母细胞瘤的晶体结构和抗癌活性

2,2-联吡啶（2,2-bpy）或1,10-菲咯啉（1,10-phen）与Bi（NO3）3·5H2O或Ce（NO3）3·6H2O的溶剂热反应调节剂提供了两个新的配位化合物[Bi2（2,2-bpy）2（BA）6]（1，HBA =苯甲酸）和[Ce（1,10-phen）Cl2] Cl（2）。两种配合物的结构已通过元素分析，红外光谱和X射线晶体衍射进行了表征。此外，两种合成复合物的抗癌活性已通过细胞计数试剂盒8（CCK-8）分析的形成进行了评估。通过逆转录聚合酶链反应（RT-PCR）检测炎症反应基因p53，nf-κb和tnf-α的相对表达。