Introduction: During routine surgery, rapid hemostasis, especially the rapid hemostasis of internal organs, is very important. The emergence of in-situ electrospinning technology has fundamentally solved this problem. It exhibits a high speed of hemostasis, and no bleeding occurs after surgery. Thus, it is of great significance. The use of sutures in some human organs, such as the intestines and bladder, is inadequate because fluid leakage occurs due to the presence of pinholes.
Methods: Three types of large intestine wounds with an opening of about 1 cm were investigated. They were untreated, treated by needle and threaded, and treated by hand-held electrospinning, respectively.
Results: The results show that hand-held electrospinning technique effectively prevented the exudation of fluids in the intestinal tract. The average diameter of the nanofibrous membrane was about 0.5 μm with hole of several micrometers. It can be elongated 90% without breakage. The hand-held electrospinning device could be used with nitrile gloves, preventing the risk of infection caused by exposed hands.
Discussion: This work can provide a reference for future animal experiments and clinical experiments. However, safety should be investigated before application.

Keywords: electrospinning, hemostasis, nanofibers


中文翻译：

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原位静电纺丝用于肠道止血。


简介：在常规手术中，快速止血，特别是内脏器官的快速止血非常重要。原位静电纺丝技术的出现从根本上解决了这一问题。止血速度快，术后不出血。由此可见，其意义重大。在某些人体器官（例如肠和膀胱）中使用缝合线是不够的，因为由于针孔的存在而发生液体渗漏。

方法：对三种类型的开口约1cm的大肠伤口进行检查。它们分别未经处理、针线处理和手持式静电纺丝处理。

结果：结果表明，手持式静电纺丝技术有效阻止了肠道内液体的渗出。纳米纤维膜的平均直径约为0.5μm，孔径为数微米。它可以伸长90%而不断裂。手持式静电纺丝装置可搭配丁腈手套使用，防止双手暴露造成感染的风险。

讨论：本工作可为今后的动物实验和临床实验提供参考。但使用前应进行安全性调查。


关键词：静电纺丝，止血，纳米纤维