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Astaxanthin in Liver Health and Disease: A Potential Therapeutic Agent.
Drug Design, Development and Therapy ( IF 4.7 ) Pub Date : 2020-06-09 , DOI: 10.2147/dddt.s230749
Jingjing Li 1 , Chuanyong Guo 2 , Jianye Wu 1
Affiliation  

Abstract: Astaxanthin is a carotenoid derived from oxygen-containing non-vitamin A sources and is mainly obtained from marine organisms. Studies have demonstrated that astaxanthin is a natural antioxidant product and it is widely used in the fields of medicine, health-care products and cosmetics. Studies have shown that astaxanthin has important preventive and therapeutic effects on liver fibrosis, non-alcoholic fatty liver, liver cancer, drug and ischemia-induced liver injury, and its mechanism is related to antioxidant and anti-inflammatory activities, and the regulation of multiple signaling pathways. In this review, we discuss the latest data on astaxanthin in the prevention and treatment of liver diseases. An understanding of the structure, source and mechanism of action of astaxanthin in the body would not only provide a theoretical basis for its clinical application but could also have important significance in screening and improving related compounds for the treatment of liver diseases.

Keywords: astaxanthin, liver diseases, antioxidants, inflammation, anticancer


中文翻译:

肝脏健康与疾病中的虾青素:一种潜在的治疗剂。

摘要:虾青素是一种类胡萝卜素,衍生自含氧的非维生素A来源,主要来自海洋生物。研究表明,虾青素是一种天然的抗氧化剂产品,广泛用于医药,保健品和化妆品领域。研究表明,虾青素对肝纤维化,非酒精性脂肪肝,肝癌,药物和缺血性肝损伤具有重要的预防和治疗作用,其机制与抗氧化和抗炎活性有关,并且对多种疾病的调节信号通路。在这篇综述中,我们讨论了虾青素在肝病预防和治疗中的最新数据。了解结构,

关键词:虾青素,肝脏疾病,抗氧化剂,炎症,抗癌
更新日期:2020-06-09
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