Water-soluble chitosan and wood pulp fiber–based nonwovens were produced using wet-laying technology, and their properties were investigated for the potential application for severe hemorrhage. The pores of the wood pulp nonwovens were completely covered as the concentration of chitosan was increased. A phosphate buffer solution uptake of 997% was attained in the nonwoven loaded with chitosan concentration of 1.5 w/v%. The deposition of blood cells was found to increase with an increase in the water-soluble chitosan concentration. The blood-clotting time was found to be 170 s, making the developed nonwoven to promote blood-clotting mechanism by creating mechanical barrier to reduce the blood loss.

中文翻译：

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一锅法合成纤维素基非织造织物与壳聚糖用于止血剂应用

使用湿法成网技术生产水溶性壳聚糖和木浆纤维基非织造布，并研究了它们的性能，以用于严重出血的潜在应用。随着壳聚糖浓度的增加，木浆非织造布的孔隙被完全覆盖。在负载浓度为 1.5 w/v% 的壳聚糖的无纺布中，磷酸盐缓冲溶液的吸收率为 997%。发现血细胞的沉积随着水溶性壳聚糖浓度的增加而增加。发现凝血时间为 170 秒，使得开发的无纺布通过创建机械屏障来减少失血来促进凝血机制。