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Pachytene piRNAs as beneficial regulators or a defense system gone rogue.
Nature Genetics ( IF 31.7 ) Pub Date : 2020-06-29 , DOI: 10.1038/s41588-020-0656-8
Alexei A Aravin 1
Affiliation  

Pachytene Piwi-interacting RNAs (piRNAs) are abundant small non-coding RNAs expressed in mammalian germ lines. A new study indicates that, among the diverse pool of piRNA sequences, a small number act as highly selective guides that induce cleavage of coding and non-coding transcripts, thus promoting piRNA generation and regulating gene expression.

中文翻译:

厚皮的piRNA作为有益的调节剂或防御系统流​​氓。

Pachytene Piwi相互作用RNA(piRNA)是在哺乳动物种系中表达的大量小的非编码RNA。一项新的研究表明,在各种piRNA序列库中,少数充当了高度选择性的向导,可诱导编码和非编码转录本的裂解,从而促进piRNA的产生和基因表达的调控。
更新日期:2020-06-29
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