Adjunctive antidepressant treatment among 763 outpatients with bipolar disorder: Findings from the Bipolar CHOICE and LiTMUS trials,Depression and Anxiety

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Adjunctive antidepressant treatment among 763 outpatients with bipolar disorder: Findings from the Bipolar CHOICE and LiTMUS trials
Depression and Anxiety ( IF 4.7 ) Pub Date : 2020-06-29 , DOI: 10.1002/da.23069
Ole Köhler-Forsberg _{1,

2,

3,

4} , Louisa G Sylvia _{3,

4} , Vicki Fung _{4,

5} , Lindsay Overhage _{4,

5} , Michael Thase ₆ , Joseph R Calabrese ₇ , Thilo Deckersbach _{3,

4} , Mauricio Tohen ₈ , Charles L Bowden ₉ , Melvin McInnis ₁₀ , James H Kocsis ₁₁ , Edward S Friedman ₁₂ , Terence A Ketter ₁₃ , Susan L McElroy _{14,

15} , Richard C Shelton ₁₆ , Michael J Ostacher ₁₃ , Dan V Iosifescu _{3,

4} , Andrew A Nierenberg _{3,

4}

Affiliation

Psychosis Research Unit and the Department of Affective Disorders, Aarhus University Psychiatry Hospital, Aarhus, Denmark.
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Dauten Family Center for Bipolar Treatment Innovation, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.
Department of Medicine, Harvard Medical School, Boston, Massachusetts.
Health Policy Research Center, Mongan Institute, Massachusetts General Hospital, Boston, Massachusetts.
Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania.
Department of Psychiatry, Case Western Reserve University, Cleveland, Ohio.
Department of Psychiatry, University of New Mexico Health Sciences Center, Albuquerque, New Mexico.
Department of Psychiatry, University of Texas Health Science Center, San Antonio, Texas.
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan.
Department of Psychiatry, Weill Cornell Medical College, New York, New York.
Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California.
Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio.
Department of Psychiatry, Lindner Center of HOPE, Mason, Ohio.
Department of Psychiatry, University of Alabama at Birmingham, Birmingham, Alabama.

Adjunctive antidepressants are frequently used for bipolar depression but their clinical efficacy has been studied in few trials and little is known about how co‐occurring manic symptoms affect treatment response.

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