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AIEgens: An emerging fluorescent sensing tool to aid food safety and quality control
Comprehensive Reviews in Food Science and Food Safety ( IF 12.0 ) Pub Date : 2020-06-28 , DOI: 10.1111/1541-4337.12591
Xiaolin Huang 1, 2, 3 , Qian Guo 1, 3 , Ruoyao Zhang 2 , Zheng Zhao 2 , Yuankui Leng 1, 3 , Jacky W Y Lam 2 , Yonghua Xiong 1, 3 , Ben Zhong Tang 2
Affiliation  

As a global public health problem, food safety has attracted increasing concern. To minimize the risk exposure of food to harmful ingredients, food quality and safety inspection that covers the whole process of “from farm to fork” is much desired. Fluorescent sensing is a promising and powerful screening tool for sensing hazardous substances in food and thus plays a crucial role in promoting food safety assurance. However, traditional fluorphores generally suffer the problem of aggregation‐caused quenching (ACQ) effect, which limit their application in food quality and safety inspection. In this regard, luminogens with aggregation‐induced emission property (AIEgens) showed large potential in food analysis since AIEgens effectively surmount the ACQ effect with much better detection sensitivity, accuracy, and robustness. In this contribution, we review the latest developments of food safety monitoring by AIEgens, which will focus on the molecular design of AIEgens and their sensing principles. Several examples of AIE‐based sensing applications for screening food contaminations are highlighted, and future perspectives and challenges in this emerging field are tentatively elaborated. We hope this review can motivate new research ideas and interest to aid food safety and quality control, and facilitate more collaborative endeavors to advance the state‐of‐the‐art sensing developments and reduce actual translational gap between laboratory research and industrial production.

中文翻译:

AIEgens:一种新兴的荧光传感工具,有助于食品安全和质量控制

食品安全作为一个全球性的公共卫生问题,越来越受到人们的关注。为了尽量减少食品暴露于有害成分的风险,食品质量安全检验涵盖“从农场到餐桌”的全过程是非常必要的。荧光传感是一种很有前景且功能强大的检测食品中有害物质的筛选工具,因此在促进食品安全保障方面发挥着至关重要的作用。然而,传统的荧光团普遍存在聚集引起猝灭(ACQ)效应的问题,这限制了它们在食品质量和安全检测中的应用。在这方面,具有聚集诱导发射特性的发光原 (AIEgens) 在食品分析中显示出巨大的潜力,因为 AIEgens 以更好的检测灵敏度、准确性和稳健性有效地克服了 ACQ 效应。在这个贡献中,我们回顾了 AIEgens 食品安全监测的最新进展,将重点介绍 AIEgens 的分子设计及其传感原理。重点介绍了几个基于 AIE 传感应用的食品污染筛查示例,并初步阐述了这一新兴领域的未来前景和挑战。我们希望这篇综述能够激发新的研究思路和兴趣,以帮助食品安全和质量控制,并促进更多的合作努力,以推进最先进的传感发展,减少实验室研究和工业生产之间的实际转化差距。重点介绍了几个基于 AIE 传感应用的食品污染筛查示例,并初步阐述了这一新兴领域的未来前景和挑战。我们希望这篇综述能够激发新的研究思路和兴趣,以帮助食品安全和质量控制,并促进更多的合作努力,以推进最先进的传感发展,减少实验室研究和工业生产之间的实际转化差距。重点介绍了几个基于 AIE 传感应用的食品污染筛查示例,并初步阐述了这一新兴领域的未来前景和挑战。我们希望这篇综述能够激发新的研究思路和兴趣,以帮助食品安全和质量控制,并促进更多的合作努力,以推进最先进的传感发展,减少实验室研究和工业生产之间的实际转化差距。
更新日期:2020-06-28
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