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Complete Photochemical Regulation of 8-17 DNAzyme Activity by Using Reversible DNA Photo-crosslinking.
ChemBioChem ( IF 2.6 ) Pub Date : 2020-06-28 , DOI: 10.1002/cbic.202000227
Yasuha Watanabe 1 , Kenzo Fujimoto 1
Affiliation  

An off‐and‐on relationship: DNAzyme activity has been completely inhibited by using reversible DNA photo‐crosslinking at 385 nm. The activity of the photo‐crosslinked DNAzyme with the substrate could be switched back on by irradiation at 312 nm.
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中文翻译:

通过使用可逆DNA光交联,对8-17 DNAzyme活性进行完整的光化学调节。

断断续续的关系:使用385 nm处的可逆DNA光交联已完全抑制了DNAzyme的活性。光交联的DNAzyme与底物的活性可以通过在312 nm处照射重新开启。
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更新日期:2020-06-28
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