Gastrulation is generally understood as the morphogenetic processes that result in the spatial organization of the blastomere into the three germ layers, ectoderm, mesoderm and endoderm. This review summarizes our current knowledge of the morphogenetic mechanisms in Drosophila gastrulation. In addition to the events that drive mesoderm invagination and germband elongation, we pay particular attention to other, less well-known mechanisms including midgut invagination, cephalic furrow formation, dorsal fold formation, and mesoderm layer formation. This review covers topics ranging from the identification and functional characterization of developmental and morphogenetic control genes to the analysis of the physical properties of cells and tissues and the control of cell and tissue mechanics of the morphogenetic movements in the gastrula.

中文翻译：

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黑腹果蝇原肠形成：遗传控制、细胞基础和生物力学

原肠胚形成通常被理解为导致卵裂球空间组织成三个胚层、外胚层、中胚层和内胚层的形态发生过程。这篇综述总结了我们目前对果蝇原肠胚形成的形态发生机制的了解。除了驱动中胚层内陷和胚带伸长的事件外，我们还特别关注其他鲜为人知的机制，包括中肠内陷、头沟形成、背褶形成和中胚层层形成。这篇综述涵盖的主题范围从发育和形态发生控制基因的识别和功能表征到细胞和组织的物理特性分析以及原肠胚形态发生运动的细胞和组织力学控制。