Through the peripheral modification of a first-generation polypropylene amine dendrimer two new photoactive dendrimers containing 4-dimethylamino-1,8-naphthalimide (3) and 3-bromo-4-dimethylamino-1,8-naphthalimide (4), have been obtained. Photophysical and spectral characteristics of these dendrimers were investigated in two organic solvents. We found that they absorb light in the visible spectral region and emit yellow-green fluorescence. Antimicrobial activity of dendrimers against pathogenic microorganisms has been investigated in solution and after deposition on a cotton fabric. For the first time, 1,8-naphthalimide derivatives have been tested as active components in antibacterial photodynamic therapy. To clarify the dendrimer effect, the results obtained were compared with those from two monomeric 1,8-naphthalimides (1 and 2) containing the same substitutes in the chromophore system. Cytotoxicity and antiviral activity of the dendrimers were also assessed.

通过对第一代聚丙烯胺树状聚合物的外围修饰，两个新的光敏树状聚合物包含4-二甲基氨基-1,8-萘二甲酰亚胺（3）和3-溴-4-二甲基氨基-1,8-萘二甲酰亚胺（4）），已获得。在两种有机溶剂中研究了这些树枝状聚合物的光物理和光谱特性。我们发现它们吸收可见光谱区域的光并发出黄绿色荧光。在溶液中和沉积在棉织物上之后，已经研究了树枝状大分子对病原微生物的抗菌活性。首次将1,8-萘二甲酰亚胺衍生物作为抗菌光动力疗法中的活性成分进行了测试。为了阐明树枝状聚合物的作用，将所得结果与发色团体系中含有相同取代基的两种单体1,8-萘二甲酰亚胺（1和2）的结果进行了比较。还评估了树状聚合物的细胞毒性和抗病毒活性。