We read with interest the paper by Perosa et al. (2020) entitled ‘Hippocampal vascular reserve associated with cognitive performance and hippocampal volume’. The author reported that a mixed blood supply of the hippocampus by the posterior cerebral artery (PCA) and anterior choroidal artery (AChA) may provide vascular reserve and protect against cognitive impairment. The work is novel and critically important, given the relevance of hippocampal injury in Alzheimer’s dementia and other cognitive disorders. It is unclear, however, how the authors accounted for the heterogeneous configuration of the circle of Willis in their methods. There is no mention of the role that another anterior circulation artery,...

中文翻译：

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威利斯环的异质性及其在海马灌注中的意义。

我们感兴趣地阅读了 Perosa等。（2020）题为“与认知能力和海马体积有关的海马血管储备”。作者报告说，大脑后动脉（PCA）和脉络膜前动脉（AChA）混合供应海马可能提供血管储备并防止认知障碍。鉴于阿尔茨海默氏痴呆症和其他认知障碍中海马损伤的相关性，这项工作是新颖且至关重要的。然而，尚不清楚作者如何在他们的方法中解释威利斯环的异质构造。没有提及另一条前循环动脉的作用...