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Soluble immune checkpoints CTLA-4, HLA-G, PD-1, and PD-L1 are associated with endometriosis-related infertility.
American Journal of Reproductive Immunology ( IF 2.5 ) Pub Date : 2020-06-27 , DOI: 10.1111/aji.13296 Budi Santoso 1 , Ashon Sa'adi 1 , Sri Ratna Dwiningsih 1 , Arif Tunjungseto 1 , Muhammad Yohanes Ardianta Widyanugraha 1 , Alfin Firasy Mufid 1 , Nanda Yuli Rahmawati 1 , Fadhil Ahsan 1, 2
American Journal of Reproductive Immunology ( IF 2.5 ) Pub Date : 2020-06-27 , DOI: 10.1111/aji.13296 Budi Santoso 1 , Ashon Sa'adi 1 , Sri Ratna Dwiningsih 1 , Arif Tunjungseto 1 , Muhammad Yohanes Ardianta Widyanugraha 1 , Alfin Firasy Mufid 1 , Nanda Yuli Rahmawati 1 , Fadhil Ahsan 1, 2
Affiliation
Soluble immune checkpoint molecules constitute the emerging novel mediators in immune regulation. Their role in the pathogenesis of endometriosis has not been fully addressed. In this study, we aimed to investigate the relationship between the clinical manifestation of endometriosis‐associated infertility and the level of four soluble immune checkpoints: sCTLA4, sHLA‐G, sPD‐1, and sPD‐L1.
中文翻译：
可溶性免疫检查点 CTLA-4、HLA-G、PD-1 和 PD-L1 与子宫内膜异位症相关的不孕症有关。
可溶性免疫检查点分子构成了免疫调节中新兴的新型介质。它们在子宫内膜异位症发病机制中的作用尚未完全解决。本研究旨在探讨子宫内膜异位症相关不孕症的临床表现与四种可溶性免疫检查点水平之间的关系：sCTLA4、sHLA-G、sPD-1和sPD-L1。
更新日期：2020-06-27
中文翻译：
可溶性免疫检查点 CTLA-4、HLA-G、PD-1 和 PD-L1 与子宫内膜异位症相关的不孕症有关。
可溶性免疫检查点分子构成了免疫调节中新兴的新型介质。它们在子宫内膜异位症发病机制中的作用尚未完全解决。本研究旨在探讨子宫内膜异位症相关不孕症的临床表现与四种可溶性免疫检查点水平之间的关系：sCTLA4、sHLA-G、sPD-1和sPD-L1。
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