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Antitumor and hepatoprotective activity of natural and synthetic neo steroids.
Progress in Lipid Research ( IF 14.0 ) Pub Date : 2020-06-27 , DOI: 10.1016/j.plipres.2020.101048
Valery M Dembitsky 1
Affiliation  

In this review, steroids with a tertiary butyl group, which are usually called neo steroids, are a small group of natural lipids isolated from higher plants, fungi, marine sponges, and yeast. In addition, steroids with a tertiary butyl group have been synthesized in some laboratories in Canada, USA, Europe, and Japan and their biological activity was studied. Some natural neo steroids demonstrate antitumor or hepatoprotective activities. In addition, synthetic neo steroids exhibit anticancer and neuroprotective properties. However, to confirm the above data, both practical and clinical experimental studies are necessary. Nevertheless, the results may be useful for pharmacologists, chemists, biochemists, and the pharmaceutical industry.



中文翻译:

天然和合成新类固醇的抗肿瘤和保肝活性。

在这篇综述中,具有叔丁基的类固醇通常被称为新类固醇,是从高等植物,真菌,海洋海绵和酵母中分离出的一小类天然脂质。另外,在加拿大,美国,欧洲和日本的一些实验室中已经合成了具有叔丁基的甾族化合物,并对其生物学活性进行了研究。一些天然的新类固醇具有抗肿瘤或保肝作用。另外,合成的新类固醇具有抗癌和神经保护特性。但是,要确认上述数据,必须进行实践和临床实验研究。但是,该结果对于药理学家,化学家,生物化学家和制药行业可能有用。

更新日期:2020-06-27
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