The visual system is an important biological indicator of effects induced by ultraviolet (UV) radiation. However, research has extensively investigated the effects of high-dose UV radiation in a single exposure, thus, the differential of this work was to investigate the effects of UVB radiation in low doses in single and repeated exposure. Therefore, we investigated the effects of repeated exposure to environmental UVB doses (0.09 J/cm²) on the retina and optic lobes of the crab Neohelice granulata. We evaluated the reactive oxygen species (ROS) concentration, antioxidant capacity against peroxyl radicals (ACAP) levels, catalase (CAT) and glutathione S-transferase (GST) activities and lipoperoxidation (LPO) levels and performed histological analysis. The crabs were exposed to UVB radiation for 1 or 60 days, while the control group was exposed to visible light. In the retina region, increases in ROS concentration and CAT and GST activities after the single exposure were observed. After 60 days of exposure, we observed an increase in ACAP levels. In the optic lobes, we observed an increase in GST activity and a decrease in LPO levels after the single exposure. However, we observed an increase in ROS concentration after 60 days of exposure. Moreover, after 60 days of exposure, infiltrating hemocytes in the retina and disorganization in neuron cell bodies of the external medulla were observed. In this sense, single and repeated exposure to low doses of UVB radiation induced changes in oxidative status and inflammatory process in the visual system of the crab Neohelice granulata.

视觉系统是由紫外线（UV）辐射引起的影响的重要生物学指标。但是，研究已经广泛研究了高剂量紫外线辐射在单次照射中的作用，因此，这项工作的不同之处在于研究低剂量紫外线辐射在单次和重复照射中的作用。因此，我们研究了反复暴露于环境UVB剂量（0.09 J / cm ²）对蟹新鳞片视网膜和视裂的影响。。我们评估了活性氧（ROS）的浓度，抗过氧自由基（ACAP）的抗氧化能力，过氧化氢酶（CAT）和谷胱甘肽S-转移酶（GST）活性和脂过氧化（LPO）的水平，并进行了组织学分析。螃蟹暴露于UVB辐射1或60天，而对照组暴露于可见光。在视网膜区域，单次暴露后观察到ROS浓度以及CAT和GST活性增加。暴露60天后，我们观察到ACAP水平升高。在视叶中，我们观察到单次暴露后GST活性增加，LPO水平降低。但是，我们观察到暴露60天后ROS浓度增加。而且，暴露60天后，观察到视网膜中浸润的血细胞和外延髓的神经元细胞体的紊乱。从这个意义上讲，一次或多次暴露于低剂量的UVB辐射下会导致蟹的视觉系统氧化状态和炎症过程的变化。新螺旋体颗粒。