Abstract The emergence of new virulent Vibrio strains resistant to common antibiotics has caused significant economic losses to shrimp farming worldwide. It is mandatory to adopt new strategies to control shrimp farming related vibriosis. Essential oils (EOs) have several biological properties among of which the quorum sensing (QS) inhibitory activity is appealing for vibriosis control. In this work, we evaluated QS inhibitory activity of five EOs obtained from oregano (Organum vulgare), tea tree (Melaleuca alternifolia), lemongrass (Cymbopogon citratus), cinnamon (Cinnamomum verum) and thyme (Thymus vulgaris), at sublethal doses. EOs involvement in bioluminescence shutdown, biofilm formation and swarming motility was evaluated in four Vibrio strains of aquaculture interest including V. harveyi, V. campbellii, V. vulnificus, and V. parahaemolyticus. Oregano oil (EOOv) and tea tree oil (EOMa) were further tested in in vivo assays due to their significant effects (P

中文翻译：

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精油介导的抗病毒治疗南美白对虾弧菌病

摘要 对常见抗生素具有抗性的新剧毒弧菌菌株的出现给全球对虾养殖造成了重大经济损失。必须采用新的策略来控制与虾养殖相关的弧菌病。精油 (EO) 具有多种生物学特性，其中群体感应 (QS) 抑制活性对弧菌病控制具有吸引力。在这项工作中，我们评估了从牛至（Organum vulgare）、茶树（Melaleuca alternifolia）、柠檬草（Cymbopogon citratus）、肉桂（Cinnamomum verum）和百里香（Thymus vulgaris）中获得的五种 EOs 的 QS 抑制活性，亚致死剂量。在四种对水产养殖感兴趣的弧菌菌株（包括哈维弧菌、坎贝尔弧菌、创伤弧菌和弧菌弧菌）中评估了 EOs 参与生物发光关闭、生物膜形成和蜂群运动的情况。副溶血性。牛至油 (EOOv) 和茶树油 (EOMa) 由于其显着影响而在体内试验中进行了进一步测试 (P