People with epilepsy (PWE) are neither more likely to be infected by the coronavirus nor are they more likely to have severe COVID-19 manifestations because they suffer from epilepsy. However, management of COVID-19 in PWE may be more complicated than that in other individuals. Drug-drug interactions could pose significant challenges and cardiac, hepatic, or renal problems, which may happen in patients with severe COVID-19, may require adjustment to antiepileptic drugs (AEDs). In this review, we first summarize the potential drug-drug interactions between AEDs and drugs currently used in the management of COVID-19. We then summarize other challenging issues that may happen in PWE, who have COVID-19 and are receiving treatment.

癫痫患者 (PWE) 既不太可能感染冠状病毒，也不太可能出现严重的 COVID-19 表现，因为他们患有癫痫症。然而，PWE 中 COVID-19 的管理可能比其他个体更复杂。药物-药物相互作用可能带来重大挑战，严重 COVID-19 患者可能出现心脏、肝脏或肾脏问题，可能需要调整抗癫痫药物 (AED)。在这篇综述中，我们首先总结了 AED 和目前用于 COVID-19 管理的药物之间潜在的药物相互作用。然后，我们总结了 PWE 中可能发生的其他具有挑战性的问题，他们患有 COVID-19 并正在接受治疗。