Abstract

A naturally biodegradable, reusable, and eco-safe catalyst, i.e., uric acid was developed and exploited for the green, facile and economical one-pot synthesis of pyran annulated heterocyclic systems from starting materials. This method gives an insight into the credibility of pathway followed by the aforementioned green and reusable catalyst in aiding the heterocyclic compounds formation. High atom economy, cleaner reaction profile, simple column-free work up condition, shorter reaction times, high to excellent yields, eco-safe and high catalytic activity make this present procedure an interesting alternative to the multistep approaches.

中文翻译：

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尿酸作为一种天然可生物降解和可重复使用的催化剂，用于方便和生态安全地合成具有生物活性的吡喃环杂环体系

摘要

一种可自然生物降解、可重复使用和生态安全的催化剂（即尿酸）被开发和开发用于从起始材料绿色、简便且经济的一锅法合成吡喃环化杂环体系。该方法可以深入了解上述绿色和可重复使用的催化剂在帮助杂环化合物形成中所遵循的途径的可信度。高原子经济性、更清洁的反应曲线、简单的无柱后处理条件、更短的反应时间、高至极好的产率、生态安全和高催化活性使该现有程序成为多步方法的有趣替代方案。