Five new and one unsual known bioactive compounds have been isolated from the methanol extract of Kuji amber which was subjected to silica gel column chromatography in order to yield lipophilic compounds.　A new clerodane derivative, named Kujione A (15-nor-2-oxo-3-cleroden-13-ol), was isolated from the medium polar fractions.　This was done using Kujione A’s growth-restoring activity against a mutant Saccharomyces cerevisiae strain (zds1Δ erg3Δ pdr1/3Δ) that is hypersensitive with respect to Ca²⁺-signal transduction. The structure was elucidated by spectroscopic data, HREIMS, along with 1D- and 2D-NMR, among others. 15-norclerodane has been categorized as a new and distinct compound because it has a conjugated carbonyl functional group; it has not been found in isolated constituents from Kuji amber.

已经从苦瓜琥珀的甲醇提取物中分离出五种新的和一种罕见的生物活性化合物，将其进行硅胶柱色谱分析以产生亲脂性化合物。从中等极性组分中分离出一种新的环戊烷衍生物，名为Kujione A（15-nor-2-oxo-3-cleroden-13-ol）。这使用Kujione A的生长恢复活性对突变进行酿酒酵母株（zds1 Δ ERG3 Δ PDR1 / 3 Δ）是过敏相对于Ca² ⁺-信号转导。通过光谱数据HREIMS以及1D-NMR和2D-NMR阐明了该结构。15-正环烷烷由于具有共轭的羰基官能团而被归类为新的独特化合物。在来自久慈琥珀的分离成分中尚未发现。