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Nanocellulose for Stabilization of Pickering Emulsions and Delivery of Nutraceuticals and Its Interfacial Adsorption Mechanism
Food and Bioprocess Technology ( IF 5.3 ) Pub Date : 2020-06-27 , DOI: 10.1007/s11947-020-02481-2
Shima Saffarionpour

Nanocellulose proved to be an efficient material for the preparation of Pickering emulsions with potential for replacing synthetic surfactants, which show toxic effects in the gastrointestinal (GI) tract. Its self-assembling capability, tensile strength, and stiffness make it an efficient material for stabilization of emulsions. Nanoemulsion systems stabilized with nanocellulose (NC) can be prepared for delivery of nutraceuticals with therapeutic utilities and achieving their controlled release in the GI tract. Stable emulsions can be produced even when the surface of droplets is covered by a low amount of NCs. Hydrophobic modification of NCs enhances their dispersibility in nonpolar solvents, and modification with cationic surfactants enables the production of emulsions with transitional phase inversion and production of water-in-oil emulsions. Grafting NCs with responsive polymers provides the opportunity of producing smart emulsifiers for delivery of nutraceuticals. The adsorption of NCs at the interfaces is influenced by their surface chemistry and charge and the emulsion conditions such as pH, temperature, and ionic strength. Their adsorption can be explained based on particle diffusion to the interface and charge-induced kinetic adsorption barrier. Modification of NCs allows achieving faster adsorption and higher surface pressure and surface coverage. Considering the economic and environmental benefits of NCs in replacing nonrenewable materials and their potential in producing stable Pickering emulsions, this review aims to highlight recent studies on the application of NCs for stabilization of Pickering emulsions and delivery of nutraceuticals, and discusses their interfacial adsorption mechanism, influenced by processing conditions, providing insights to food and drug manufacturers.



中文翻译:

纳米纤维素稳定Pickering乳剂和营养食品的输送及其界面吸附机理

纳米纤维素被证明是用于制备Pickering乳液的有效材料,具有替代合成表面活性剂的潜力,该合成表面活性剂在胃肠道(GI)中显示出毒性作用。它的自组装能力,拉伸强度和刚度使其成为稳定乳液的有效材料。可以制备用纳米纤维素(NC)稳定的纳米乳剂体系,以递送具有治疗用途的营养保健品并实现其在胃肠道中的受控释放。即使液滴表面被少量的NC覆盖,也可以产生稳定的乳液。NCs的疏水改性可提高其在非极性溶剂中的分散性,而阳离子表面活性剂的改性可实现具有过渡相转化的乳液的生产以及油包水型乳液的生产。用响应性聚合物接枝NCs提供了生产智能乳化剂以输送营养保健品的机会。NCs在界面上的吸附受其表面化学性质和电荷以及乳液条件(例如pH,温度和离子强度)的影响。它们的吸附可以基于粒子向界面的扩散和电荷诱导的动力学吸附势垒来解释。NC的改性可以实现更快的吸附以及更高的表面压力和表面覆盖率。考虑到NCs替代不可再生材料的经济和环境效益及其在生产稳定的Pickering乳剂中的潜力,因此,本综述旨在重点介绍有关NCs在Pickering乳剂稳定化和营养保健品中的应用的最新研究,

更新日期:2020-06-27
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