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Nanocomposite hydrogels for tissue engineering applications.
Nanoscale ( IF 5.8 ) Pub Date : 2020-06-26 , DOI: 10.1039/d0nr03785k
Hongbo Zhao 1 , Min Liu 2 , Yajie Zhang 3 , Jingbo Yin 4 , Renjun Pei 3
Affiliation  

Tissue engineering is an important field of regenerative medicine, which combines scaffolds and cell transplantation to develop substitute tissues and/or promote tissue regeneration. Hydrogels, a three-dimensional network with high water content and biocompatibility, have been widely used as scaffolds to mimic the structure and properties of tissues. However, the low mechanical strength and limited functions of traditional hydrogels greatly limited their applications in tissue engineering. Recently, nanocomposite hydrogels, with its advantages of high mechanical property and some unique properties (such as electrical conductivity, antibacterial, antioxidation, magnetic responsiveness), have emerged as the most versatile and innovative technology, which provides a new opportunity as a unique tool for fabricating hydrogels with excellent properties. In this review, we summarize the recent advances in fabricating nanocomposite hydrogels and their applications in tissue engineering. In addition, the future and prospects of nanocomposite hydrogels for tissue engineering are also discussed.

中文翻译:

用于组织工程应用的纳米复合水凝胶。

组织工程学是再生医学的重要领域,其将支架和细胞移植结合以发展替代组织和/或促进组织再生。具有高水含量和生物相容性的三维网络水凝胶已被广泛用作模仿组织结构和特性的支架。然而,传统水凝胶的低机械强度和有限的功能极大地限制了它们在组织工程中的应用。近年来,具有高机械性能和某些独特性能(例如导电性,抗菌性,抗氧化性,磁响应性)的优点的纳米复合水凝胶已成为最通用和创新的技术,这为作为一种独特的工具提供了新的机遇。制备具有优异性能的水凝胶。在这篇综述中,我们总结了制备纳米复合水凝胶的最新进展及其在组织工程中的应用。此外,还讨论了用于组织工程的纳米复合水凝胶的前景和前景。
更新日期:2020-07-23
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