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Rapid Induction of Female-to-Male Sex Change in Adult Zebrafish by Injection of an Aromatase Inhibitor.
Zebrafish ( IF 1.4 ) Pub Date : 2020-08-13 , DOI: 10.1089/zeb.2020.1864
Md Mostafizur Rahaman 1 , Ryo-Ichi Kumagai 2 , Toshinobu Tokumoto 1, 2
Affiliation  

Previously, we examined whether aromatase inhibitor (AI) treatment induces a sex change in adult female zebrafish. A 5-month AI treatment regime resulted in the retraction of the ovaries and testis formation. Eight weeks after changing the diet to AI-free food, a large number of normal sperm were obtained. Artificial fertilization using sperm from the sex-changed females was successful. These results demonstrated that sex plasticity remains in the mature ovaries of zebrafish. However, >7 months of treatment was necessary; thus, pairing was unsuccessful.

中文翻译:

通过注射芳香化酶抑制剂快速诱导成年斑马鱼雌雄性别的变化。

以前,我们检查了芳香化酶抑制剂(AI)处理是否在成年雌性斑马鱼中引起了性别变化。5个月的AI治疗方案导致卵巢和睾丸缩回。将饮食改为不含AI的食物后八周,获得了大量的正常精子。使用来自变性女性的精子进行人工受精成功。这些结果表明,性可塑性保留在斑马鱼的成熟卵巢中。但是,必须> 7个月的治疗;因此,配对失败。
更新日期:2020-08-17
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