Previously, we examined whether aromatase inhibitor (AI) treatment induces a sex change in adult female zebrafish. A 5-month AI treatment regime resulted in the retraction of the ovaries and testis formation. Eight weeks after changing the diet to AI-free food, a large number of normal sperm were obtained. Artificial fertilization using sperm from the sex-changed females was successful. These results demonstrated that sex plasticity remains in the mature ovaries of zebrafish. However, >7 months of treatment was necessary; thus, pairing was unsuccessful.

中文翻译：

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通过注射芳香化酶抑制剂快速诱导成年斑马鱼雌雄性别的变化。

以前，我们检查了芳香化酶抑制剂（AI）处理是否在成年雌性斑马鱼中引起了性别变化。5个月的AI治疗方案导致卵巢和睾丸缩回。将饮食改为不含AI的食物后八周，获得了大量的正常精子。使用来自变性女性的精子进行人工受精成功。这些结果表明，性可塑性保留在斑马鱼的成熟卵巢中。但是，必须> 7个月的治疗；因此，配对失败。