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Single-Laboratory Validation Study of a Proton NMR Method for the Determination of L-Arginine, L-Citrulline, and Taurine Contents in Dietary Supplements
Journal of AOAC INTERNATIONAL ( IF 1.6 ) Pub Date : 2020-06-24 , DOI: 10.1093/jaoacint/qsaa002
Isaac Lee 1 , Jennie Vo 1 , Quanyin Gao 1 , Piyush Purohit 1 , Veronica Zarraga 1 , Silva Babajanian 2 , Peter Chang 3 , Gary Swanson 3
Affiliation  

A quantitative NMR (qNMR) method can provide rapid analysis compared to chromatographic methods. Sample preparation steps are relatively simpler and run time is shorter. Rapid analysis methods for release tests in quality control laboratories are very important for laboratory efficiency. Here, we describe a single-laboratory validation study for a rapid qNMR analysis of L-arginine, L-citrulline, and taurine in powdered and tablet dietary supplement products.

中文翻译:

质子NMR法测定膳食补充剂中L-精氨酸,L-瓜氨酸和牛磺酸含量的单实验室验证研究

与色谱方法相比,定量NMR(qNMR)方法可以提供快速分析。样品制备步骤相对简单,运行时间较短。质量控制实验室中用于释放测试的快速分析方法对于实验室效率非常重要。在这里,我们描述了一种单实验室验证研究,用于粉状和片状膳食补充剂产品中L-精氨酸,L-瓜氨酸和牛磺酸的快速qNMR分析。
更新日期:2020-07-30
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