Implementation of EUCAST susceptibility testing in an Australian hospital laboratory demonstrated higher rates of aminopenicillin and amoxicillin/clavulanate resistance in Haemophilus influenzae than previously recognized. This study aimed to better define the variability in the detection of β-lactam resistance based on EUCAST and CLSI disc diffusion (DD) methodology, by comparison with the recommended reference method, broth microdilution (BMD), and by concordance with genomic analysis.

中文翻译：

---

评估流感嗜血杆菌EUCAST和CLSI盘片扩散方法以识别氨基青霉素和阿莫西林/克拉维酸耐药性。

澳大利亚一家医院实验室对EUCAST药敏试验的实施表明，流感嗜血杆菌中氨苄青霉素和阿莫西林/克拉维酸耐药性的发生率高于以前的认识。这项研究旨在通过与推荐的参考方法肉汤微稀释法（BMD）进行比较，并与基因组分析相一致，基于EUCAST和CLSI圆盘扩散（DD）方法更好地定义检测β-内酰胺抗性的变异性。