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Diversity of energy metabolism in immune responses regulated by micro-organisms and dietary nutrition.
International Immunology ( IF 4.4 ) Pub Date : 2020-03-27 , DOI: 10.1093/intimm/dxaa020
Koji Hosomi 1 , Jun Kunisawa 1, 2, 3, 4
Affiliation  

Immune metabolism has been recognized as a new paradigm in the regulation of host immunity. In the environment, there are many micro-organisms including pathogenic and non-pathogenic and/or beneficial ones. Immune cells exhibit various responses against different types of microbes, which seem to be associated with changes in energy metabolism. In addition, dietary nutrition influences host metabolism and consequent responses by immune cells. In this review, we describe the complex network of immune metabolism from the perspectives of nutrition, micro-organisms and host immunity for the control of immunologic health and diseases.

中文翻译:

微生物和饮食营养调节免疫反应中能量代谢的多样性。

免疫代谢已被认为是调节宿主免疫力的新范例。在环境中,存在许多微生物,包括病原性和非病原性和/或有益微生物。免疫细胞对不同类型的微生物表现出各种反应,这似乎与能量代谢的变化有关。此外,饮食营养会影响宿主的新陈代谢,进而影响免疫细胞的反应。在这篇综述中,我们从营养,微生物和宿主免疫的角度描述了免疫代谢的复杂网络,以控制免疫健康和疾病。
更新日期:2020-03-27
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