Abstract Rheum tanguticum is a traditional Chinese herbal medicine, which contains abundant anthraquinones. In this study, anthraquinones were efficiently extracted from Rheum tanguticum by subcritical water extraction (SWE). The parameters of extraction time (33–67 min), temperature (100–200°C), and SW flow rate (1.4–4.6 mL/min) were optimized so as to achieve a high yield of the target product. A high yield of the total anthraquinones was achieved under the optimized SWE conditions of extraction time 54 min, extraction temperature 170°C, and the flow rate 2.0 mL/min. The comparison between the SWE and traditional extraction techniques implied that the SWE is an efficient and green alternative method for the extraction of anthraquinones. Four anthraquinone glycosides were purified from the SWE extract by high-speed counter-current chromatography and identified as emodin-1-O-β-D-glucoside, physcion-8-O-β-D-glucopyranoside, chrysophanol-1-O-β-D-glucoside, and chrysophanol-8-O-β-D-glucoside.

中文翻译：

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一种利用亚临界水从大黄中提取蒽醌的绿色策略

摘要 唐古大黄是一种传统的中草药，含有丰富的蒽醌类化合物。在这项研究中，通过亚临界水萃取 (SWE) 从大黄中有效地提取了蒽醌类化合物。优化萃取时间（33–67 min）、温度（100–200°C）和 SW 流速（1.4–4.6 mL/min）等参数，以实现目标产物的高收率。在提取时间为 54 min、提取温度为 170°C、流速为 2.0 mL/min 的优化 SWE 条件下，总蒽醌的收率很高。SWE 与传统提取技术的比较表明 SWE 是一种高效、绿色的蒽醌提取方法。