Journal of Trace Elements in Medicine and Biology ( IF 3.6 ) Pub Date : 2020-06-26 , DOI: 10.1016/j.jtemb.2020.126602 R Constance Wiener 1 , Ruchi Bhandari 2
Background
Exposure of toxic metals from e-cigarette use is a cause for public health concern because youth, young adults, and non-smokers are the target population rapidly adopting e-cigarette use. The purpose of this research is to determine the association of the body burden of heavy metals with e-cigarette use using NHANES (U.S.) 2015–2016 data.
Methods
Blood lead (N = 1899) and urinary cadmium, barium, and antimony (N = 1302) data were extracted from NHANES, 2015–2016; geometric means were calculated and bivariate and multivariable linear regression analyses were conducted. Participants were categorized as having neither e-cigarette nor cigarette use; smoking history (including dual use with e-cigarettes); and only e-cigarette (current or former).
Results
In multivariable analyses adjusted for sex, race/ethnicity, age, and poverty levels, current or former e-cigarette use failed to reach a statistical significance in the association with metals. However, participants with a smoking history were more likely to have higher blood lead and urinary cadmium than participants who neither used e-cigarettes nor cigarettes.
Conclusion
Blood lead levels, and urinary cadmium, barium, and antimony levels were similar between participants who used e-cigarettes and participants who did not.
中文翻译:
电子烟使用与铅、镉、钡和锑身体负担的关联:NHANES 2015-2016。
背景
使用电子烟接触到有毒金属是引起公众健康问题的一个原因,因为年轻人、年轻人和非吸烟者是迅速采用电子烟使用的目标人群。本研究的目的是使用 NHANES(美国)2015-2016 年的数据确定重金属的身体负担与电子烟使用之间的关联。
方法
血铅 (N = 1899) 和尿镉、钡和锑 (N = 1302) 数据来自 NHANES,2015-2016 年;计算几何平均值并进行双变量和多变量线性回归分析。参与者被归类为既不使用电子烟也不使用香烟;吸烟史(包括电子烟双重使用);并且只有电子烟(当前或以前)。
结果
在针对性别、种族/民族、年龄和贫困水平进行调整的多变量分析中,当前或以前的电子烟使用在与金属的关联方面未能达到统计显着性。然而,与既不使用电子烟也不吸烟的参与者相比,有吸烟史的参与者更可能有更高的血铅和尿镉。
结论
使用电子烟的参与者和不使用电子烟的参与者的血铅水平以及尿镉、钡和锑水平相似。