Herein, we described the modification of chitosan with cyanuric chloride as a mediator for preparation of chitosan-s-triazinyl-bis(2-aminomethylpyridine) and chitosan-s-triazinyl-bis(8-oxyquinoline) derivatives to be used as reagents for preparation of silver nanoparticles under ecofriendly conditions. These two reagents are convenient and effective for reduction of silver ions to silver nanoparticles with particle size less than 10 nm that might be suitable for industrial and medicinal applications. The formation and particle size of AgNPs are characterized by transmission electron microscopy (TEM), X-ray diffraction (XRD), scanning electron microscope (SEM), and energy-dispersive X-ray analysis (EDX). The antimicrobial activity of the two modified chitosan-s-triazine-AgNPs was evaluated against activities against Gram-positive bacteria (M. luteus ATCC 10240 and MRSA ATCC 43300), Gram-negative bacteria (E. coli ATCC 25922 and P. aeruginosa ATCC 75853), and C. albicans. The results showed that chitosan-s-triazinyl-bis(2-aminomethylpyridine) AgNPs showed high antimicrobial activities against all the tested microorganisms, while their analogous chitosan-s-triazinyl-bis(8-oxyquinoline) AgNPs showed moderate activities.

中文翻译：

---

壳聚糖-S-三嗪基-双（2-氨基甲基吡啶）和壳聚糖-S-三嗪基-双（8-羟基喹啉）衍生物：用于制备银纳米颗粒的新试剂及其抗菌评价效果

在此，我们描述了用氰尿酰氯作为介体对壳聚糖进行改性，用于制备壳聚糖-s-三嗪基-双（2-氨基甲基吡啶）和壳聚糖-s-三嗪基-双（8-羟基喹啉）衍生物，用作制备试剂环境友好条件下的银纳米粒子。这两种试剂可方便有效地将银离子还原为粒径小于 10 nm 的银纳米颗粒，可能适用于工业和医药应用。AgNPs 的形成和粒径通过透射电子显微镜 (TEM)、X 射线衍射 (XRD)、扫描电子显微镜 (SEM) 和能量色散 X 射线分析 (EDX) 进行表征。评估了两种改性壳聚糖-s-三嗪-AgNPs 对革兰氏阳性菌（M. luteus ATCC 10240 和 MRSA ATCC 43300）、革兰氏阴性菌（大肠杆菌 ATCC 25922 和铜绿假单胞菌 ATCC 75853）和白色念珠菌。结果表明，壳聚糖-s-三嗪基-双（2-氨基甲基吡啶）AgNPs 对所有测试微生物均显示出高抗菌活性，而其类似的壳聚糖-s-三嗪基-双（8-羟基喹啉）AgNPs 则显示出中等活性。