Oxylipins are oxidized compounds of polyunsaturated fatty acids that play important roles in the body. Recently, metabololipidomic-based studies using advanced mass spectrometry have measured the oxylipins generated during acute and chronic physical exercise and described the related physiological effects. The objective of this systematic review was to provide a panel of the primary exercise-related oxylipins and their respective functions in healthy individuals. Searches were performed in five databases (Cochrane, PubMed, Science Direct, Scopus and Web of Science) using combinations of the Medical Subject Headings (MeSH) terms: “Humans”, “Exercise”, “Physical Activity”, “Sports”, “Oxylipins”, and “Lipid Mediators”. An adapted scoring system created in a previous study from our group was used to rate the quality of the studies. Nine studies were included after examining 1749 documents. Seven studies focused on the acute effect of physical exercise while two studies determined the effects of exercise training on the oxylipin profile. Numerous oxylipins are mobilized during intensive and prolonged exercise, with most related to the inflammatory process, immune function, tissue repair, cardiovascular and renal functions, and oxidative stress.

中文翻译：

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氧脂素对急性和慢性运动的反应：系统评价。

氧脂质是多不饱和脂肪酸的氧化化合物，在体内发挥重要作用。最近，使用先进质谱法的基于代谢脂组学的研究测量了急性和慢性体育锻炼期间产生的氧脂素，并描述了相关的生理效应。本系统评价的目的是提供一组与运动相关的主要氧脂质及其在健康个体中各自的功能。使用医学主题词 (MeSH) 术语的组合在五个数据库（Cochrane、PubMed、Science Direct、Scopus 和 Web of Science）中进行搜索：“Humans”、“Exercise”、“Physical Activity”、“Sports”、“ Oxylipins”和“脂质介质”。我们小组在之前的一项研究中创建了一个改编的评分系统，用于评估研究的质量。在检查了 1749 份文件后，纳入了 9 项研究。七项研究侧重于体育锻炼的急性影响，而两项研究则确定了运动训练对氧脂质谱的影响。在剧烈和长时间的运动过程中，大量的氧脂素会被动员起来，其中大多数与炎症过程、免疫功能、组织修复、心血管和肾功能以及氧化应激有关。