This Account summarizes our involvement in the development of dearomatization reactions of indoles that has for origin a total synthesis problematic. We present the effort from our group to obtain 3D-indolines scaffold from the umpolung of N-acyl indoles via activation with FeCl3 to the oxidative spirocyclizations of N-EWG indoles and via the use of electrochemistry. 1 Introduction 2 Activation of N-Acyl Indoles with FeCl3 2.1 Hydroarylation of N-Acyl Indoles 2.2 Difunctionalization of N-Acyl Indoles 3 Radical-Mediated Dearomatization of Indoles for the Synthesis of Spirocyclic Indolines 4 Electrochemical Dearomatization of Indoles 4.1 Direct Electrochemical Oxidation of Indoles 4.2 Indirect Electrochemical Oxidation of Indoles 5 Conclusion

中文翻译：

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吲哚的脱芳构化反应获得 3D 二氢吲哚结构

该帐户总结了我们参与开发吲哚的脱芳构化反应的过程，该反应的起源是全合成问题。我们展示了我们小组的努力，通过用 FeCl3 活化到 N-EWG 吲哚的氧化螺环化和通过使用电化学从 N-酰基吲哚的 umpolung 获得 3D-二氢吲哚支架。1 引言 2 用 FeCl3 活化 N-酰基吲哚 2.1 N-酰基吲哚的加氢芳基化 2.2 N-酰基吲哚的双官能化 3 自由基介导的吲哚脱芳构化合成螺环二氢吲哚 4 吲哚的电化学脱芳构化 4.1 吲哚的直接电化学脱芳 2.2 吲哚的直接电化学反应吲哚的间接电化学氧化 5 结论