The lipid component of Alzheimer's disease research

L. M. Munter

This editorial highlights the work by Kaya et al. suggesting that focal lipid perturbations occur at the amyloid plaque, a pathological hallmark of Alzheimer's disease. The disruption of lipid homeostasis could form the basis of myelin degeneration in Alzheimer's disease, possibly through the recruitment of the apolipoprotein E (ApoE), a strong risk factor of the disease.

Read the highlighted article on page 84 and the full Editorial Highlight on page 7.

中文翻译：

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发行信息

阿尔茨海默氏病研究中的脂质成分

LM·芒特

这篇社论重点介绍了Kaya等人的工作。提示局部脂质扰动发生在淀粉样斑块上，这是阿尔茨海默氏病的病理学特征。脂质稳态的破坏可能形成阿尔茨海默氏病髓磷脂变性的基础，可能是通过招募载脂蛋白E（ApoE）引起的，该蛋白是该病的一个高风险因素。

阅读第84页的突出显示的文章和第7页的完整的编辑要点。