Adipose tissue–derived microvascular fragments serve as natural vascularization units in angiogenesis research and tissue engineering due to their ability to rapidly reassemble into microvascular networks. Recent studies indicate that they exhibit additional unique properties that may be beneficial for a wide range of future biomedical applications. Their angiogenic activity can be increased during short-term cultivation as a means of adapting their vascularization capacity to patient-specific needs. Moreover, they are a source of endothelial progenitor cells, multipotent mesenchymal stromal cells, and lymphatic vessel fragments. Finally, they exert immunomodulatory effects, determining the tissue integration of implanted biomaterials. Hence, microvascular fragments represent versatile building blocks for the improvement of vascularization, organotypic tissue formation, lymphatic regeneration, and implant integration.

脂肪组织衍生的微血管碎片由于能够快速重新组装成微血管网络，因此在血管生成研究和组织工程中可作为天然血管形成单位。最近的研究表明，它们表现出额外的独特特性，可能有利于未来广泛的生物医学应用。它们的血管生成活性可以在短期培养期间增加，作为使它们的血管化能力适应患者特定需求的一种手段。此外，它们是内皮祖细胞、多能间充质基质细胞和淋巴管碎片的来源。最后，它们发挥免疫调节作用，决定植入生物材料的组织整合。因此，微血管碎片代表了用于改善血管化的通用构件，