Peroxynitrite (ONOO⁻), as one type of reactive nitrogen species (RNS), is closely related to multiple pathophysiological processes. Visualization of ONOO⁻ in living system is essential for further study of its physiological functions. However, most existing ONOO⁻ fluorescent probes continuously display the aggregation-caused quenching (ACQ). In present research, a new activatable AIEgen fluorescent probe QM-ONOO⁻ for ONOO⁻ recognition and imaging was proposed. Activation of the probe by ONOO⁻, induced aggregation of QM−OH. This sensor showed fast response time (<4 min) and high sensitivity (DL, 27.5 nM), large Stock's shift (190 nm), long emission wavelength. Furthermore, the outcomes indicate that QM-ONOO⁻ as an activatable AIEgen fluorescent sensor was robust chemical tool to detect endogenous peroxynitrite in living biological system.

过氧亚硝酸盐（ONOO ^- ），作为一种类型的反应性氮物种的（RNS ），是密切相关的多个病理生理过程。ONOO的可视化^-在生活系统是其生理功能进一步的研究是必不可少的。然而，大多数现有ONOO ^-的荧光探针连续地显示聚合引起的淬灭（ACQ）。在目前的研究，新的激活AIEgen荧光探针QM-ONOO ^-对ONOO ^-识别和成像提出。通过ONOO激活探针^-，导致QM-OH聚集。该传感器显示出快速响应时间（<4分钟）和高灵敏度（DL，27.5 nM），大斯托克位移（190 nm）和长发射波长。此外，结果表明，QM-ONOO ^-作为可活化的荧光AIEgen传感器是检测在活生物内源系统的过氧亚硝酸盐健壮化学工具。