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Cross sections of alpha-particle induced reactions on natNi: Production of 67Cu
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms ( IF 1.4 ) Pub Date : 2020-06-25 , DOI: 10.1016/j.nimb.2020.06.022
S. Takács , M. Aikawa , H. Haba , Y. Komori , F. Ditrói , Z. Szűcs , M. Saito , T. Murata , M. Sakaguchi , N. Ukon

The 67Cu is considered as one of the most perspective radio isotopes in targeted radio-immunotherapy medical applications. 67Cu is a β-emitter with a mean β energy, which allows treating tumors in size up to about 4 mm. Its decay is followed by emission of low energy gamma-rays suitable for gamma-camera imaging. The about three days half-life (T1/2 = 61.83 h) is optimal for human applications. However, one of the main drawback factors for its application is still the limited supply of 67Cu. There are several possibilities to produce 67Cu. High flux reactors, charged particle accelerators and high-energy bremsstrahlung radiations can be used to produce 67Cu. In this work we have studied one of the promising charged particle production routes based on the 64Ni(α,p)67Cu nuclear reaction. Cross sections for formation of 67,64,61,60Cu, 62,63Zn and 56,57Ni were studied up to 50 MeV alpha-particle energy on nickel targets with natural isotopic composition.



中文翻译:

nat Ni上的α粒子诱导反应的横截面:生成67 Cu

67铜被认为是定向的无线电免疫治疗的医疗应用的最视角放射性同位素之一。67铜为β -发射极,平均β -能量,这允许治疗肿瘤的大小达到约4mm。其衰减之后,发出适合于伽马相机成像的低能伽马射线。约三天的半衰期(T 1/2  = 61.83 h)最适合人类应用。但是,其应用的主要缺点之一仍然是67 Cu的供应有限。生产67 Cu有几种可能性。高通量反应堆,带电粒子加速器和高能致辐射可以用来产生67铜 在这项工作中,我们研究了基于64 Ni(α,p)67 Cu核反应的一种有前途的带电粒子生产路线。研究了在具有天然同位素组成的镍靶材上,形成高达50 MeVα粒子能的67,64,61,60 Cu,62,63 Zn和56,57 Ni的横截面。

更新日期:2020-06-25
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