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Synthesis of 5-Aryl(heteryl)-1-hydroxyethyl-4-(furyl-2-carbonyl)-3-hydroxy-3-pyrroline-2-ones
Russian Journal of General Chemistry ( IF 0.9 ) Pub Date : 2020-06-25 , DOI: 10.1134/s1070363220050072
V. L. Gein , D. D. Rubtsova , A. A. Bobyleva , A. N. Yankin

Abstract

5-Aryl(heteryl)-1-hydroxyethyl-4-(furyl-2-carbonyl)-3-hydroxy-3-pyrroline-2-ones were synthesized via reactions of methyl ester of furyl-2-carbonylpyruvic acid with a mixture of aromatic or heterocyclic aldehyde and ethanolamine in dioxane. Antibacterial and antifungal activities of the synthesized compounds was studied.


中文翻译:

5-芳基(杂基)-1-羟乙基-4-(呋喃基-2-羰基)-3-羟基-3-吡咯啉-2-酮的合成

摘要

通过呋喃基-2-羰基丙酮酸的甲基酯与甲基丙烯酸的混合物反应,合成了5-芳基(杂基)-1-羟乙基-4-(呋喃基-2-羰基)-3-羟基-3-吡咯啉-2-酮。二恶烷中的芳族或杂环醛和乙醇胺。研究了合成化合物的抗菌和抗真菌活性。
更新日期:2020-06-25
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