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Auxiliary role of mesenchymal stem cells as regenerative medicine soldiers to attenuate inflammatory processes of severe acute respiratory infections caused by COVID-19.
Cell and Tissue Banking ( IF 1.4 ) Pub Date : 2020-06-25 , DOI: 10.1007/s10561-020-09842-3
Peyvand Parhizkar Roudsari 1 , Sepideh Alavi-Moghadam 2 , Moloud Payab 3 , Forough Azam Sayahpour 4 , Hamid Reza Aghayan 2 , Parisa Goodarzi 5 , Fereshteh Mohamadi-Jahani 5 , Bagher Larijani 6 , Babak Arjmand 1, 2
Affiliation  

Acute respiratory infections as one of the most common problems of healthcare systems also can be considered as an important reason for worldwide morbidity and mortality from infectious diseases. Coronaviruses are a group of well-known respiratory viruses that can cause acute respiratory infections. At the current state, the 2019 novel coronavirus is cited as the most worldwide problematic agent for the respiratory system. According to investigations, people with old age and underlying diseases are at higher risk of 2019 novel coronavirus infection. Indeed, they may show a severe form of the disease (with severe acute respiratory infections). Based on the promising role of cell therapy and regenerative medicine approaches in the treatment of several life-threatening diseases, it seems that applying cell-based approaches can also be a hopeful strategy for improving subjects with severe acute respiratory infections caused by the 2019 novel coronavirus. Herein, due to the amazing effects of mesenchymal stem cells in the treatment of various diseases, this review focuses on the auxiliary role of mesenchymal stem cells to reduce inflammatory processes of acute respiratory infections caused by the 2019 novel coronavirus.

中文翻译:


间充质干细胞作为再生医学战士的辅助作用,可减轻由 COVID-19 引起的严重急性呼吸道感染的炎症过程。



急性呼吸道感染作为医疗保健系统最常见的问题之一,也被认为是全球传染病发病和死亡的重要原因。冠状病毒是一组众所周知的呼吸道病毒,可引起急性呼吸道感染。目前,2019 年新型冠状病毒被认为是全球范围内对呼吸系统影响最大的病原体。据调查,年老且有基础疾病的人群感染2019新型冠状病毒的风险较高。事实上,他们可能表现出严重的疾病形式(严重的急性呼吸道感染)。基于细胞疗法和再生医学方法在治疗多种危及生命的疾病中所发挥的良好作用,应用基于细胞的方法似乎也可以成为改善 2019 年新型冠状病毒引起的严重急性呼吸道感染患者的一种充满希望的策略。在此,由于间充质干细胞在治疗多种疾病中的惊人作用,本综述重点讨论间充质干细胞在减少2019新型冠状病毒引起的急性呼吸道感染炎症过程中的辅助作用。
更新日期:2020-06-25
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