Anterior prefrontal cortex (PFC; Brodmann area 10) activations are often, but not always, found in neuroimaging studies investigating deception, and the precise role of this area remains unclear. To explore the role of PFC in face-to-face deception, we invited pairs of participants to play a card game involving lying and lie detection while we used functional near infrared spectroscopy (fNIRS) to record brain activity in PFC. Participants could win points for successfully lying about the value of their cards or for detecting lies. We contrasted patterns of brain activation when the participants either told the truth or lied, when they were either forced into this or did so voluntarily, and when they either succeeded or failed to detect a lie. Activation in anterior PFC was found in both lie production and detection, unrelated to reward. Analysis of cross-brain activation patterns between participants identified areas of PFC where the lead player’s brain activity was synchronized their partner’s later brain activity. These results suggest that during situations that involve close interpersonal interaction, anterior PFC supports processing widely involved in deception, possibly relating to the demands of monitoring one’s own, and other people’s behaviour.

中文翻译：

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fNIRS测量前额叶皮层（区域10）在面对面欺骗中的作用。

前额叶前皮层（PFC； Brodmann区域10）的激活在神经影像学研究中经常（但并非总是）被发现在欺骗方面，并且该区域的确切作用仍不清楚。为了探索PFC在面对面欺骗中的作用，我们邀请成对参与者玩纸牌游戏，其中包括说谎和说谎检测，同时我们使用功能性近红外光谱（fNIRS）记录PFC中的大脑活动。参与者可能会因成功撒谎或撒谎而赢得积分。当参与者说出真相或撒谎，被强迫或自愿撒谎，成功或未能发现谎言时，我们对比了大脑激活的方式。在产卵和检测中都发现前PFC的激活，与报酬无关。参与者之间的跨脑激活模式的分析确定了PFC的区域，在该区域中，主玩家的大脑活动与对方的后期大脑活动同步。这些结果表明，在涉及密切人际互动的情况下，前部PFC支持广泛参与欺骗的处理，这可能与监视自己和他人行为的需求有关。