Abstract

Objective

The aim of this study was to investigate the effects of exercise training on ventricular repolarization dynamicity and heart rate variability in chronic heart failure patients.

Design

A total of 22 chronic heart failure patients with reduced ejection fraction in sinus rhythm were included in the study. The patients were in NYHA classes II–III with an ejection fraction of 29.7 ± 7.7%. Before and after 4 weeks of aerobic exercise training, all patients performed a cardiopulmonary exercise test, a standard twelve-lead electrocardiogram and a 24 h Holter recording from which heart rate variability and ventricular repolarization dynamicity were assessed.

Results

We observed a significant decrease of QTpeak (p < .001) and QTend (p < .001) at RR intervals ranging from 600 to 1000 ms on 24 h QT/RR regressions after 4 weeks of exercise training. Our analyses revealed that short-term exercise training induced significant changes in the frequency and time domain HRV parameters on an overall time-period of 24 h.

Conclusion

Four weeks of exercise training induced significant changes in ventricular repolarization dynamicity in chronic heart failure patients. In addition, short-term exercise training was enough to improve patients’ heart rate variability.

中文翻译：

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慢性心力衰竭患者进行四周运动训练后心室复极变化的观察。

摘要

目的

这项研究的目的是调查运动训练对慢性心力衰竭患者心室复极动态性和心率变异性的影响。

设计

该研究共纳入22例窦性心律射血分数降低的慢性心力衰竭患者。患者属于NYHA II-III级，射血分数为29.7±7.7％。在进行有氧运动训练4周之前和之后，所有患者均进行了心肺运动测试，标准的十二导联心电图和24小时动态心电图记录，从中评估了心率变异性和心室复极动态。

结果

我们观察到 ，在运动训练4周后的24小时QT / RR回归中，RR间隔600至1000 ms时，QTpeak（p  <.001）和QTend（p <.001）显着下降。我们的分析显示，短期运动训练在24小时的整个时间段内引起了频率和时域HRV参数的显着变化。

结论

进行为期四周的运动训练后，慢性心力衰竭患者的心室复极动态发生了显着变化。此外，短期运动训练足以改善患者的心率变异性。