In recent times the impact of pharmaceutical wastes generated from the pharmaceutical industry and domestic sewages on the aquatic ecosystem has become a major concern. The traditional sole treatment processes are not adequate for the elimination of these wastes. To overcome the lack of the individual treatment processes, integrated treatment methodology has been devised in the present study. The degradation of the pharmaceutical, levosulpiride, by using Ozone (O₃), activated carbon (AC) and biological treatment by A.faecalis JF339228 and E. aurantiacum KX008295.1in its aqueous solution has been investigated. The percentage removal of Levosulpiride from its synthetic aqueous solution of 600 mg/L concentration using 2 g/L activated carbon and 5.2 g/h ozone and biological treatment by A.faecalis JF339228 and E. aurantiacum KX008295.1 in 72 hr were 51.60, 53.50, 39.97, and 37.51% respectively. Simultaneous treatment using adsorption and ozone followed by biological treatment with A. faecalis JF339228 and E. aurantiacum KX008295.1 has been employed in this study. To overcome the demerits of the individual treatment process, the integrated treatment is employed which has shown a synergistic effect in the degradation of levosulpiride with minimal doses of activated carbon, ozone, and minimum time of operation. The percentage removal of levosulpiride achieved was about 76 and 61% for 800 mg/L levosulpiride wastewater, respectively. Therefore, the integrated treatment system is rendered economical, efficient, and safe.

中文翻译：

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使用先进的综合处理策略，包括物理，化学和生物处理，从制药废水中去除左旋磺酰脲

近年来，制药行业产生的制药废物和生活污水对水生生态系统的影响已成为主要问题。传统的单一处理工艺不足以消除这些废物。为了克服个别治疗方法的不足，本研究已设计出综合治疗方法。制药，levosulpiride的降解，通过使用臭氧（O ₃），活性炭（AC）和生物处理由A.faecalis JF339228和E.橙黄已经研究了KX008295.1在其水溶液中的含量。使用2 g / L活性炭和5.2 g / h臭氧从600 mg / L浓度的合成水溶液中除去左旋舒必利的百分数为51.60，采用A.faecalis JF339228和E. aurantiacum KX008295.1对其进行生物处理， 53.50％，39.97％和37.51％。使用的吸附和臭氧的同时处理，随后生物处理与粪JF339228和E.橙黄KX008295.1已被用于这项研究。为了克服单个处理方法的缺点，采用了综合处理，该处理在最小剂量的活性炭，臭氧和最少的操作时间下对左旋磺酰脲的降解显示出协同作用。对于800 mg / L的左旋磺酰脲废水，去除的左旋磺酰脲百分比分别约为76％和61％。因此，使综合处理系统经济，有效和安全。