The present study assessed the effects of intramammary infusion of Bifidobacterium breve (B. breve ) on mastitis‐causing pathogens and on the somatic cell counts (SCC) in lactating cows with chronic subclinical mastitis. The bacteriological cure rates of 42 quarters from 42 cows infected with Staphylococcus aureus, Corynebacterium bovis , coagulase‐negative staphylococci, and environmental streptococci were 18.2% (2/11), 14.3% (1/7), 58.8% (10/17), and 28.6% (2/7), respectively, on day 14 after B. breve infusion. In a second trial, B. breve was infused into 18 quarters from 18 cows with chronic subclinical mastitis from which pathogens had not been isolated; the rates of quarters showing SCC > 50 × 10⁴ cells/ml prior to B. breve infusion that decreased to < 30 × 10⁴ cells/ml after infusion were significantly (p < .01) increased to 61.1% (11/18) on day 14 compared to that prior to infusion (0/18). The intramammary infusion of B. breve appears to be a non‐antibiotic approach for elimination of minor pathogens and decreasing SCC in quarters with chronic subclinical mastitis in dairy cows.

中文翻译：

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乳房内输注短双歧杆菌对慢性亚临床乳腺炎奶牛乳腺炎病原体和体细胞反应的影响。

本研究评估了乳房内输注短双歧杆菌( B. breve ) 对乳腺炎病原体和慢性亚临床乳腺炎泌乳牛体细胞计数 (SCC) 的影响。感染金黄色葡萄球菌、牛棒状杆菌、凝固酶阴性葡萄球菌、环境链球菌的42头奶牛42个季度细菌学治愈率分别为18.2%（2/11）、14.3%（1/7）、58.8%（10/17）和 28.6% (2/7)，分别在B. breve输注后第 14 天。在第二项试验中，将 18 头未分离出病原体的慢性亚临床乳腺炎奶牛的B. breve注入 18 个区域；显示 SCC > 50 × 10 的季度比率与输注前相比，在第 14 天输注后下降至 < 30 × 10 ^{4 个}细胞/ ml^的短双歧杆菌输注前 4 个细胞/ml 显着 (p < .01) 增加至 61.1% (11/18)（ 0/18）。B. breve的乳房内输注似乎是一种非抗生素方法，用于消除轻微病原体和减少奶牛慢性亚临床乳腺炎的 SCC。