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Antiviral mechanisms of candidate chemical medicines and traditional Chinese medicines for SARS-CoV-2 infection.
Virus Research ( IF 2.5 ) Pub Date : 2020-06-24 , DOI: 10.1016/j.virusres.2020.198073
Chang Li 1 , Lin Wang 2 , Linzhu Ren 3
Affiliation  

The Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly become a global pandemic. Up to now, numerous medicines have been applied or approved for the prevention and control of the virus infection. However, the efficiency of each medicine or combination is completely different or still unknown. In this review, we discuss the types, characteristics, antiviral mechanisms, and shortcomings of recommended candidate medicines for SARS-CoV-2 infection, as well as perspectives of the drugs for the disease treatment, which may provide a theoretical basis for drug screening and application.



中文翻译:

候选化学药物和中药治疗 SARS-CoV-2 感染的抗病毒机制。

由严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2) 引起的 2019 年冠状病毒病 (COVID-19) 已迅速成为全球大流行病。截至目前,已有多种药物被应用或批准用于预防和控制病毒感染。然而,每种药物或组合的功效完全不同或仍然未知。在这篇综述中,我们讨论了推荐的治疗SARS-CoV-2感染候选药物的类型、特点、抗病毒机制和缺点,以及药物治疗疾病的前景,为药物筛选和治疗提供理论依据。应用。

更新日期:2020-06-26
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