Background

We report a case of fatal congenital toxoplasmosis with maternal infection dated four months before pregnancy in the absence of any specific immunosuppressive condition.

Case

Ms. D. experienced submaxillary lymphadenitis in February 2018. The medical workup performed revealed an acute T. gondii infection. She became pregnant in June 2018 while she still had adenopathy. The second obstetrical ultrasound, performed at 16 weeks of pregnancy, revealed a fetal death. The research for T. gondii by PCR was positive in the products of conception.

Conclusion

Diagnosis of toxoplasmosis should be discussed in case of miscarriage with lymphadenitis. As lymph nodes in T. gondii infection could be responsible for iterative release of parasites and fetal death, symptomatic toxoplasmosis should be treated in women of childbearing age.

中文翻译：

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妊娠前四个月发生的先天性弓形虫病流产合并孕妇感染。

背景

我们报告了一例致命的先天性弓形虫病，其母体感染发生在怀孕前四个月，没有任何特定的免疫抑制情况。

案件

D.女士于2018年2月经历了上颌下淋巴结炎。进行的医学检查显示为急性刚地弓形虫感染。她于2018年6月怀孕，当时她仍患有腺病。怀孕16周时进行的第二次产科超声检查发现胎儿死亡。PCR对刚地弓形虫的研究在构想产物上是积极的。

结论

如果流产合并淋巴结炎，应讨论弓形虫病的诊断。由于刚地弓形虫感染的淋巴结可能是寄生虫反复释放和胎儿死亡的原因，所以育龄妇女应治疗有症状的弓形虫病。