In modern society, the use of cosmetics has increased extensively; unfortunately, so-called several toxic metal salts are present as the colorant or filler in cosmetics. The ferrous ion (Fe²⁺) is one of the metal ions used in cosmetics as a colorant. Ferrous ion (Fe²⁺) is a vital component in live cells. Considering the adverse effect of high doses of ferrous ions in cosmetics and live cells, we developed a turn-on fluorescent probe P_Fe(II) for quantitative estimation of ferrous ion (Fe²⁺) in cosmetics and monitoring of labile ferrous (Fe²⁺) ion in live cells. The fluorescent probe P_Fe(II) showed a visual color change from colorless to orange in the presence of ferrous ion (Fe²⁺) in the cosmetics. We observed that UV-absorption increased at 390 nm upon incubation with ferrous ion (Fe²⁺). The probe P_Fe(II) has provided quantitative information on ferrous ion (Fe²⁺) in various cosmetics, kajol, lip balm, face foundation, mascara, eyeliner, lipliner, face makeup, sindoor, lipstick, nail polish in ppm level through the fluorescence signaling at 460 nm.The probe P_Fe(II) provided information on labile Fe²⁺ ion pool via a fluorescence imaging. It is a new addition to the diagnostic inventory for detecting ferrous ion in live cells and cosmetics.

在现代社会中，化妆品的使用已广泛增加。不幸的是，所谓的几种有毒金属盐作为化妆品中的着色剂或填充剂存在。亚铁离子（Fe ²⁺）是化妆品中用作着色剂的金属离子之一。亚铁离子（Fe ²⁺）是活细胞中的重要成分。考虑到高剂量亚铁离子对化妆品和活细胞的不利影响，我们开发了一种开启式荧光探针P _Fe（II）用于定量估计化妆品中亚铁离子（Fe ²⁺）和监测不稳定的亚铁（Fe ^{2 +}）活细胞中的离子。荧光探针P _{Fe（II ）}在化妆品中存在亚铁离子（Fe ²⁺）时，显示出从无色到橙色的视觉颜色变化。我们观察到，与亚铁离子（Fe ²⁺）孵育后，紫外线吸收在390 nm处增加。探针P _{Fe（II ）}提供了ppm级以下各种化妆品，kajol，润唇膏，面部粉底，睫毛膏，眼线笔，lipliner，脸部化妆品，sindoor，口红和指甲油中的亚铁离子（Fe ²⁺）的定量信息。460 nm处的荧光信号。探针P _Fe（II）提供了有关不稳定Fe ^2+的信息离子池通过荧光成像。它是用于诊断活细胞和化妆品中亚铁离子的诊断清单中的新增功能。